Welcome to the online edition of the Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics . Edited by Lynn Jorde , Peter Little , Mike Dunn and Shankar Subramaniam , this is a fantastic resource that brings together for the first time all four fields of genetics, genomics, proteomics and bioinformatics in an online format for faster delivery of content to meet your dynamic research requirements.

The Browse by Contents button above takes you to the full table of contents. The articles are also classified by type, as Introductory Reviews for people new to a subject, Specialist Reviews that provide in-depth coverage for those with more experience, Short Specialist reviews that address cutting-edge topics in current research, and Basic Techniques essays or Tutorials. These may be accessed via the Browse by Subjects button.

The focus is on studies based on the human and mouse genomes, but other important model eukaryotes, as well as pathogenic bacteria, are given in-depth coverage. With articles written by established leaders in the field as well as by rising stars, this work will be an essential reference tool for all members of genomics, proteomics, transcriptomics and bioinformatics teams, from students, to post-docs, to senior scientists, and a 'must have' for university and research institute libraries. It will also provide a valuable resource for pharmaceutical and biotech companies that have an interest in this important and rapidly developing field.

New Content

The Encyclopedia will be updated regularly to reflect the ever-changing and dynamic fields of genetics, genomics, proteomics and bioinformatics. In December 2006 the following articles were added:

• Epigenetic Variation: Amount, Causes and Consequences [Section 1.3]
• Importance of complex traits [Section 1.5]
• Functional annotation of the mouse genome: the challenge of phenotyping [Section 2.4]
• Orbitrap mass analyzer [Section 3.1]
• InterPro [Section 3.6]
• Attacking Performance Bottlenecks [Section 4.8]

In October 2006 the following articles were added:

• Quantitative EM techniques [Section 3.4]
• Glycosylation in renal cancer [Section 3.5]
• Glycosylation and hepatacellular carcinoma [Section 3.5]
• The PRINTS protein fingerprint database: functional and evolutionary applications [Section 3.6]
• PANTHER: Protein families and subfamilies modeled on the divergence of function [Section 3.6]
• GRID technologies [Section 4.8]

In July 2006 the following articles were added:

• Consequences of error [Section 1.4]
• Impact of linkage disequilibrium on multipoint linkage analysis [Section 1.4]
• Digital karyotyping: a powerful tool for cancer gene discovery [Section 2.2]
• The chimpanzee genome [Section 2.4]
• Post translational modifications to plants – glycosylation [Section 3.5]
• Functional prediction through phylogenetic inference and structural classification of proteins [Section 3.6]
• Protein-ligand docking and structure-based drug design [Section 3.7]
• BioPAX - biological pathway data exchange format [Section 4.7]

The first Encyclopedia update articles were added in April 2006:

• Geographic structure of human genetic variation: medical and evolutionary implications [Section 1.1]
• Regulation of DNA methylation by Dnmt3L [Section 1.3]
• Developmental regulation of DNA methyltransferases [Section 1.3]
• Genomics of rickettsia [Section 2.5]
• Listeriae [Section 2.5]
• Advances of LC-MS and CZE-MS in proteome analysis [Section 3.1]
• Tutorial on protein fingerprinting [Section 3.1]
• Analysing proteomic, genomic and transcriptomic elemental compositions to uncover the intimate evolution of biopolymers [Section 3.3]
• Topology of protein interaction networks and cell physiology [Section 3.3]
• MAGE-OM: An object model for the communication of microarray data [Section 4.7]

For readers approaching new fields, there is a comprehensive Glossary that explains over 500 terms in a clear and concise way.

You can also buy this Major Reference Work in print format by clicking here.